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Divakar Kolhe
Divakar Kolhe

Role of Ketoanalogues in Slowing Kidney Disease Progression

Ketoanalogues are widely used as part of conservative treatment strategies for chronic kidney disease. Their primary role is to reduce metabolic waste while maintaining nutritional adequacy, which can contribute to better long-term kidney outcomes.


By lowering nitrogen intake, ketoanalogues help reduce uremic toxin accumulation. This reduction may ease metabolic stress on damaged kidneys and support more stable biochemical parameters in patients adhering to low-protein diets.


Maintaining muscle mass is a critical concern in CKD management. Ketoanalogues provide essential amino acid support without promoting excessive protein breakdown. This helps preserve physical strength and overall health during long-term treatment.


In addition to metabolic benefits, ketoanalogues may also support better acid-base balance and phosphorus control when used appropriately. These factors are important in preventing complications commonly seen in kidney disease.


While ketoanalogues are not a cure, their role in slowing disease progression highlights the importance of nutritional therapy as a core component of kidney care.


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